Treatment of acne takes several forms: topical, general and physical

Treatment takes several forms.

Topical treatment

The doctor will comprehensively assess the skin condition and, depending on the type of acne, determine and suggest an appropriate treatment.

The first step of professional skin care is deep cleansing. If the person presents with large inflamed deposits, healing is preferred.

In the first stages of treatment, the application of topical preparations in the form of solutions, ointments, creams and gels is appropriate.

Table: Effects of medications

MEDICATION EFFECT
Benzoyl peroxide
  • keratolytic (breaks down the outer layer of the skin)
  • reduces the number of anaerobic propionibacteria
  • reduces the number of inflammatory manifestations
Azelaic acid
  • antiproliferative (directed against tissue proliferation),
  • cytostatic (inhibiting the growth of cells), antibacterial,
  • comedolytic (dissolving comedones ("blackheads"))
  • and antiphlogistic (anti-inflammatory) effect
Topical antibiotics (erythromycin, clindamycin)
  • suppress the growth of propionibacteria
Topical retinoids
  • comedolytic, keratolytic (removing scales) effect mild anti-inflammatory
  • and sebostatic (lesssebum, i.e. oily substance) effect

Individually prepared medications are an essential part of topical acne treatment.

They are kept in every dermatologist's office, since prescribing an individually prepared medicine gives the patient a tailor-made therapy. Acne therapy is dominated by solutions and ointments.

General treatment

If topical treatment does not achieve successful results, or if the acne progresses to a more severe degree, it is necessary to choose a combination of topical therapy with general treatment.

Acne treatment is a long-term process and requires patience on the part of the patient and adherence to the doctor's recommendations.

Table: Medications and effects

MEDICATION EFFECT
Oral antibiotics, tetracycline antibiotics (tetracycline, doxycycline, minocycline)macrolide antibiotics (erythromycin, azithromycin)
  • reduce the number of propionibacteria,
  • at the same time, there is an inhibition of lipases of propionibacteria and a decrease in free fatty acids, which are characterized by irritant potential,
  • reduction of inflammation
Isotretinoin
  • direct inhibitory effect on the sebaceous glands
  • reduction of keratinization in follicles
  • comedolytic effect
  • anti-inflammatory effect
Hormonal therapy
  • reduces the level of free androgens in the blood
  • suppresses the production of androgens

Physical and complementary treatment of acne

Physical treatment includes phototherapy.

Phototherapy uses light of a certain wavelength that absorbs protoporphyrin IX (found in bacteria and yeast). Once the light is absorbed, the protoporphyrin IX molecules are broken down, resulting in the formation of oxygen radicals that are toxic to the bacteria.

This way, the inflammatory manifestations of acne are relieved.

Another option for the physical treatment of acne is the so-called photodynamic therapy.

This method uses the synergistic effect of aminolevulinic acid (a photosensitive substance) and light of a certain wavelength (415 nm, so-called blue light, or 633 nm, so-called red light).

The result of such treatment is the apoptosis of sebaceous gland cells and the destruction of yeast and bacteria.

The Smoothbeam laser uses pulse emissions and laser energy with a wavelength of 1450 nm to reach the deeper parts of the skin where the sebaceous glands are located.

The result is a reduction in sebum production.

Cryotherapy (cooling treatment) is one of the most commonly used methods.

It is mainly indicated for the treatment of acne papulopustulosa. The surface treatment effectively relieves inflammatory manifestations and reduces sebum production.

Chemical peeling is used to treat acne comedonica, acne papulopustulosa and acne scars. After peeling, the skin is moisturized, softer and smoother.

Acne treatment
Professional and supervised treatment is important. Photo source: Getty images.
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