Treatment of hypothyroidism: Can it be cured with drugs?

Treatment for hypothyroidism involves taking a synthetic thyroid hormone called levothyroxine every day. By substituting levothyroxine, the symptoms of hypothyroidism disappear and blood tests return to normal.

Treatment is started with small doses, e.g. 12.5-25 micrograms per day. After two weeks, the dose is gradually increased to a long-term maintenance dose.

Absorption of levothyroxine may be affected by gastrointestinal disease or the use of other drugs. Dose adjustment is necessary when taking dietary supplements such as iron, calcium, when taking antiepileptic drugs such as phenytoin or carbamazepine, or when taking antibiotics such as rifampicin.

Levothyroxine is best taken fasting at the same time each day. It is best to take the medicine first thing in the morning and wait an hour before eating or taking other medicines.

Excessive doses of the hormone can cause side effects such as:

  • Increased appetite
  • insomnia
  • heart palpitations
  • trembling of the limbs
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