Chlamydia treatment: medication, antibiotics and regimen measures

The treatment outcomes of diagnosed chlamydial diseases are relatively good.

An essential factor in the treatment is adherence to the established procedure, which, in addition to pharmacotherapy, i.e. treatment with medication, also includes lifestyle changes.

• Early identification of persons with an acute attack of infection and selection of the correct treatment.
• Treatment of all sexual partners of an infected person (very important).
• Abstinence from sexual activities during treatment.
• Follow-up check, preferably with a PCR test.

Pharmacotherapy is, as in the case of other bacterial infections, based on the administration of antibiotics.

There is currently no vaccine available against species Chlamydia trachomatis.

Antibiotic treatment must be tailored to individual patients, their clinical condition and the site of the infection, i.e. targeted antibiotic treatment.

Choosing the right antibiotic depends on its properties and behaviour in the body.

• It must be sufficiently stable in the environment of the body's cells.
• It must have the ability to achieve sufficient tissue concentration at the site of infection.
• It must have the ability to bind to the chlamydial microbial cell.
• It must have the ability to penetrate bacterial cells well.
• It must have a sufficient duration of action.
• It must kill chlamydia cells and thus prevent them from multiplying.
• It must not attack healthy tissue cells.

The retreat of the symptoms of the disease during treatment does not mean

that the bacterium in the body is completely eliminated. The treatment must

be long enough to not only suppress the symptoms of infection, but also to

actually destroy the bacteria.

Antibiotics can be given during monotherapy, i.e. treatment with only one type of antibiotic, combinations of several types of antibiotics, or in special forms of administration.

One of them is intermittent therapy with a break of several days between each cycle of treatment. Another form is called prolonged treatment where the antibiotic is taken for a longer period of time (several weeks).

Table: Overview of antibiotics used to treat chlamydial infections

In addition to genital infectious diseases caused by Chlamydia trachomatis, other chlamydial infections are quite common, too.

One of them is upper and lower respiratory tract infection, caused by the bacterial species Chlamydophila pneumoniae, mainly affecting humans.